Compounded tirzepatide dosing schedule, units per dose and storage: the reference page.

Tirzepatide is injected once a week. The FDA-approved label for Zepbound starts at 2.5 mg weekly for four weeks, then increases in 2.5 mg steps at intervals of at least four weeks, up to a maximum of 15 mg weekly. Clinicians often hold a dose longer than four weeks if side effects need to settle; moving up is a clinical decision, not a calendar one. At SkinnyVIP the price is identical at every step, so there is never a financial reason to move faster or slower than your body wants.

Units assume a standard U-100 insulin syringe (100 units = 1 mL). Compounded vials come in several concentrations; read the strength on your label and use the formula below rather than assuming.

Units to draw = (your dose in mg ÷ vial concentration in mg/mL) × 100.

Example: 5 mg from a 10 mg/mL vial = (5 ÷ 10) × 100 = 50 units. Example: 7.5 mg from a 20 mg/mL vial = (7.5 ÷ 20) × 100 = 37.5 units. If a number comes out between the marks on your syringe, ask your clinician or pharmacist which way to round; do not guess.

Two things people get wrong: reading "mg" on the label as if it were the whole vial's content when it is per mL, and using a 0.3 mL or 0.5 mL syringe whose marks are not in standard units. If you are unsure which syringe you have, send us a photo of it.

Per the Zepbound label, if a dose is missed, take it within 4 days (96 hours) of the scheduled day; if more than 4 days have passed, skip it and take the next dose on the regular day. Do not take two doses within 3 days of each other. If you have missed two or more weeks, message your clinician before restarting; the dose may need to step back down.

Refrigerate at 36°F to 46°F (2°C to 8°C). Do not freeze; a vial that has frozen should not be used.

Beyond-use date. Compounded vials carry a beyond-use date set by the pharmacy, which is usually shorter than a manufactured product's expiry. It is printed on your label; it is the date that matters, not a number you read online. (For comparison, Lilly's label allows Zepbound to sit unrefrigerated up to 86°F for a maximum of 21 days; your compounded vial's rule is whatever its label says.)

On arrival. Vials ship cold-packed, and the package sometimes arrives with the cold packs melted and the vial feeling slightly warm. That is normal in transit and the medication is safe to use: put it in the refrigerator as soon as it is delivered. Do not let a delivery sit on a porch or in a hot car.

Each injection. New syringe every time, swab the vial top and the skin, rotate sites (abdomen, thigh, back of upper arm), and inspect the solution: it should be clear, with no cloudiness or floating particles. A pink or red tinge is normal when the pharmacy adds vitamin B12 or B6; cloudiness or particles means do not use it and message us.

Travel. An insulated pouch with a cold pack keeps a vial in range for a day; longer trips need a refrigerator at the destination.

Nausea, constipation and fatigue are the common ones, usually around dose increases. Holding the current dose for another two to four weeks is a normal clinical move, and at SkinnyVIP it costs nothing extra. If nausea is interfering with eating or sleeping, message us; the clinician can adjust the plan and, where appropriate, prescribe supportive medication. Severe abdominal pain, persistent vomiting, or signs of an allergic reaction need urgent in-person care.

How SkinnyVIP handles this. Every prescription comes from a licensed clinician who has reviewed your health history; prescription is not guaranteed. We work only with state-licensed 503A compounding pharmacies, and your medication arrives labeled with the dispensing pharmacy's name and license information as the law requires, so you can verify it yourself. You can ask us which pharmacy filled your prescription and for the lot documentation that pharmacy provides. Compounded medications are not FDA-approved products. $695 for a 3-month plan (about $232 a month) or $350 for one month, the same at every dose, no membership, nothing renews.